BDBM22796 1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indole-2,3-dione::Isatin-based compound, 16::cid_1901244

SMILES Clc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1Cl

InChI Key InChIKey=KGRJPLRFGLMQMV-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22796   

TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22796(1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indo...)
Affinity DataKi:  31nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
St. Jude Research Hospital

LigandPNGBDBM22796(1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indo...)
Affinity DataKi:  65nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed